Nanchang Wanhua Biochem Products CO.,LTD

Product introduction

NO.1  Urokinase CAS NO：9039-53-6

Urokinase is a highly specific alkaline protease isolated from the urine of healthy men. The molecular weight is mainly composed of 33000 and 54000 whose isoelectric point is PH 8 ~ 9. Urokinase powder made by the steps of extraction process of urine after silica gel adsorption, ammonium sulfate precipitation, filtration, Chromatography purification, sterilization, freeze drying , soluble in water, alkaline protease is a highly specific.

Urokinase is a kind of enzyme thrombolytic agent, which can activate plasminogen into plasmin, which can hydrolyze fibrin to form thrombus. It is mainly used in the treatment of acute myocardial infarction, acute cerebral thrombosis and cerebral embolism, peripheral arterial and venous thrombosis, central retinal artery and vein thrombosis and other fresh thrombotic occlusive diseases. For formation, peripheral vascular embolism, central retinal vein embolism, acute myocardial infarction and other fresh thromboembolic disease in the treatment of cerebral thrombosis, and renal transplantation, plastic surgery and thrombosis.

　NO.2  Aprotinin CAS NO：9087-70-1

Aprotinin, also known as Bovine pancreatic inhibitor BPTI , Kallikrein inhibitor , etc.. Its molecular formula is C284H432N84O79S7, which is a basic polypeptide chain containing 58 amino acid residues. Its molecular weight is 6.5KD (6511.44), and the isoelectric point is about 10.5.

Aprotinin is a white or slightly yellow powder, odorless, soluble in water, soluble in 70% ethanol and 50% acetone, and so on ，available dialysis .

Aprotinin is an inhibitor of serine proteases, which are used primarily for the treatment and prevention of pancreatitis; for the treatment of acute bleeding; for the treatment of shock; for the prevention of intestinal adhesion.

This product is extracted from the cattle lungs, acid water extraction, ammonium sulfate precipitation to obtain the crude product of Aprotinin, crude product and then acid precipitation, filtration, chromatography purification, sterilization, freeze drying of Aprotinin freeze-drying powder products.

      NO. 3 Hyaluronidase  CAS No. : 9001-54-1

This product is an enzyme extracted from mammalian testes ( Bovine/ sheep testes ). White or yellowish-white powder , soluble in water,insoluble in acetone/ ethanol /diethyl ether . It can catalyze hydrolysis of acidity mucoitin for example hyaluronic acid, produce oligosaccharide( mainly butyl sugar), significantly reduce the viscosity of hyaluronicacid, to reduce viscosity of tissue fluid , improving the permeability ofcapillaries and tissuse , accelerating the diffusion of intracellular andextracellular substances , so it is an important drug dispersant .

Hyaluronidase can be used as proteolytic enzyme . Used to accelerate theabsorption of intramuscular and subcutaneous injection drugs , alleviate painat injection site , promoting infiltration of local anesthetics , it isconducive to promoting the dissipation of local edema or hematoma afteroperation and trauma , it is also used for intestinal adhesions . This

product was obtained by testis extraction , salting precipitate , chromatography,remove pyrogen, freeze-drying .